This paper presents a comprehensive techno-economic analysis of heat-integrated stripper (HIS) application in chemical absorption processes for CO2 capture from flue gases, drawing insights from pilot plant studies and simulation analyses. Escalating concerns over carbon emissions prompt a growing interest in amine-based chemical absorption as a promising technology in the power industry. However, addressing energy consumption remains paramount. The HIS, integrating heat exchangers within the stripper, offers a potential solution to alleviate energy demands. Pilot tests conducted at TAURON Power Plants, utilized amobile pilot plant for amine-based 1 TPD CO2 capture. Results underwent meticulous data reconciliation, enabling evaluation of mass balances, heat losses, and process heat duty. Simulation studies conducted with the ProTreat software supported key findings from pilot studies, facilitating a detailed analysis of gas and liquid phase composition along the height of the stripper, providing insight into changes in the desorption process post-HIS application.Furthermore, a cost analysis of HIS implementation revealed an initial increase in capital costs for industrial CO2 capture plants. However, the anticipated benefits stemming from reduced heat duty are expected to yield operational cost savings, potentially offering a favourable return on investment within a reasonable time.This study contributes valuable insights into the feasibility and economic viability of HIS application in carbon capture technologies. By integrating findings from pilot studies and simulation analyses, it provides a detailed understanding of the impact of HIS on process efficiency and economic considerations. These findings inform decision-making processes and highlight the potential for HIS to play a pivotal role in enhancing the sustainability of CO2 capture processes, aiding in the transition towards a low-carbon future.